Tumori Journal (TJ) is an international peer reviewed journal centred on cancer research and clinical practice in oncology and aims to convey outstanding scientific reports covering all the facets of cancer science. TJ is committed to promoting debate in oncology through communication initiatives to foster wider dissemination of key oncology topics and advances in the scientific community.
Tumori Journal is pleased to welcome its audience to TumoursJournal.org, the embracing website that offers the opportunity for continuous updates in oncology through the insights of opinion leaders and promising researchers presented in Tumori Journal articles, podcasts and social media content.
Editor-in-Chief

Prof. Giancarlo Pruneri
Milan, Italy
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Section Editors

Luca Agnelli
Milan, Italy
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Bioinformatics/Biostatistics
Luca Agnelli is a bioinformatician at the Istituto Nazionale dei Tumori with a PhD in Experimental Hematology. In INT, he coordinates the pipelines of the institutional MTB for the management of NGS data. He is also responsible for the development of a cloud platform for the storage, analysis and monitoring of data of a network of Italian MTBs, and he coordinates the implementation and activity of INT’s High-Performance Computing platform for the analysis of NGS data.
He is involved in a series of national and international research projects, in particular the UpSmart Accelerator Award that served as basis for the development of the PROACT 2.0 tool. He co-leads one of INT’s Research Lines on “Precision Medicine and Technological Innovation”.

Fabrizio Bianchi
San Giovanni Rotondo, (FG), Italy
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Preclinical Pharmacology
Born on February 20th, 1977. Head of Cancer Biomarkers Unit. Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG). MSc in Biological Sciences (University of Milan); PhD in molecular and biological sciences (University of Milan); Master level course in Microarray and Bioinformatics (Oxford University). Work Experience: | worked as PhD student and postdoctoral fellow at the FIRC Institute for Molecular Oncology (IFOM), Milan (Italy), and then at the Program of Molecular Medicine of the European Institute of Oncology (Milan). I was a visiting scientist at the Nuffield Department of Clinical and Laboratory Sciences at University of Oxford (from 2002 to 2003). Since 2016, I am the Head of the Cancer Biomarkers Unit at the Research Hospital (IRCCS) Casa Sollievo della Sofferenza. I have several years of research experience in the fields of cancer transcriptomics and biomarkers 16 development. I have pioneered the identification of serum circulating miRNA-signature for lung cancer early detection. I am an inventor of international patentsregarding diagnostic and prognostic tools for lung cancer patients. I am an active member of the American Association for Cancer Research (AACR), the European Association for Cancer Research (EACR), the International Association for the Study of Lung Cancer (IASLC), the Italian Society for Cancer Research (AIRC), and the Italian Society of Cancerology (SIC), where I am member of the steering committee. H-index (Scopus): 28. Total number of publications: 84.
Scientific Area of Interest: lung cancer molecular biology, transcriptomics (mRNA, 25 microRNA), lung cancer biomarkers. More info:
https://operapadrepio.it/it/ricerca-scientifica/gruppi-di-ricerca/cancer-biomarkers
https://www.linkedin.com/in/fabrizio-bianchi-78223334/

Andrea Billè
London, UK
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Thoracic Oncology
Dr Andrea Billè is a thoracic Surgery consultant at Guys Hospital, London since 2015, focusing on robotic surgery and thymic malignancies. He is also associate professor at Kings College University.
Dr Andrea Billè graduated from the University of Turin, Italy in 2005. He completed his training in general thoracic surgery in 2011 and spent four years of training in Italy and one year at Guy’s Hospital in London. In July 2014 he started a clinical fellowship in thoracic surgical oncology at memorial Sloan Kettering Cancer Centre, New York. He completed his PhD in November 2015
His research activities focus on lung cancer, thymic malignancies and mesothelioma with over 100 peer reviewed publications. He was chair of the N stage for mesothelioma for 9th edition of TNM staging system
Dr Billè is a member of several international associations studying thoracic malignancies: IASLC (International Association for the Study of Lung Cancer), ESTS (European Society of Thoracic Surgeons), ITMIG (International Thymic Malignancies Interest Group).

Barbara Buldini
Padova, Italy
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Pediatric Oncology
Barbara Buldini is an internationally recognized expert of pediatric acute leukemias laboratory diagnosis and response-to-therapy monitoring.
She is Associate Professor at the University of Padova, Italy (since 2021) and serves in the managerial position of Altissima Specialità-Referente di Branca Specialistica “Leukemia Diagnosis” (since 2020).
She is the PI of the Morphology and Flow Cytometry group at the Pediatric Onco-Hematology Laboratory in Padova, the AIEOP reference laboratory for the diagnosis (immunophenotype and DNA-index) and MFC-MRD assessment of childhood acute leukemias (since 2018).
She is the scientific director of immunophenotype and MFC-MRD in ALL at first diagnosis (AIEOP-BFM ALL trials), relapse (InterALL 2010), Infant ALL, and AML (AIEOP LAM 2013) (since 2012).
She is member of numerous national and international groups/associations/societies.
She coordinates the AIEOP-BFM-AML Flow MRD group with Professor Dworzak (standardization of MFC-MRD in pediatric AML-since 2011).
She has been delegated with Professor Dworzak by the European Pediatric AML Study Group (BFM/NOPHO/LAME/AIOEP/DCOG/BSPHO/UK) for defining “Response-to-treatment/MRD Immunophenotyping” in AML (since 2012).
She is a Member of the AIEOP-BFM Flow Network, which includes the principal national reference Laboratories of BFM and AIEOP, for the standardization of immunophenotype at Diagnosis and MFC-MRD in childhood ALL (since 2006).
She leads the Padua Lab as AIEOP-BFM partner unit in the training by MFC of ALLIC Labs, groups with limited economic resources that use essentially FC for monitoring MRD in ALL treatment (Argentina and Georgia).
She is member of the Trial Steering Committee of AIEOP-BFM ALL (since 2018) and AIEOP-BFM AML 2020 (since 2019) protocols.
She was Member for AIEOP of the iLTB (international leukemia/lymphoma target board) core team, coordinated by Princes Maxima Centrum (Utrecht), for Relapsed ALL that share and discuss cases with resistant Leukemia (2021-2022).
She is Member for AIEOP of the Federal Tumorboard (since March 2023).
She is Member of the ITCC ((Innovative Therapies for Children with Cancer) Hema Committee,Villejiuf, France) (since 2021).
She is an AIEOP Member in the Ponte di Legno Group (since 2018).
She coordinates an ongoing study for the Ponte di Legno group on ALL with Hypereosinophilia (since 2023)
She is member of the Gruppo di Lavoro (GdL) AIEOP “Biologia Cellulare e Molecolare” (since 2009); consultant of the GdL AIEOP LAnL (Acute non-Lymphoblastic Leukemia – since 2012) and LLA (acute lymphoblastic leukemia – since 2018).
She was member of the Board of Directors at AIEOP (2018-2021).
She is member of TDC_AIEOP-BFM_ALL_genetics team (since 2023).
She is Tutor in the “FlowInLab project” [ https://elearning.unipd.it/flowinlab/ ], Moodle-based web site developed in collaboration with DLM Office, University of Padua as a Flow Cytometry training service (since 2016).
She participated the ‘International Project Ambi Studio’ about Ambiguous Acute Leukemias, in collaboration with iBFM FLOW network (coordinated by Prof. O. Hrusak, Praga, Czech Republic), ALLIC e St. Jude’s Children Hospital, Memphis, Tennessee, USA.
Her academic activity involves teaching Pediatrics, active member of Department Board, and supervision of graduate and PhD students.
She performed clinical track at Clinic of Pediatric Hematology-Oncology, with special interest on hemopoietic stem cell transplantation, IRCCS Policlinico San Matteo, University of Pavia, Italy, 2005-2006.
She coordinates and collaborates to several national and international projects.

Carlo Alfredo Clerici
Milan, Italy
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Psycho-Oncology
Carlo Alfredo Clerici, MD, PhD is Associate Professor of Clinical Psychology (M-PSI/08) at the University of Milan, since December 2022 and works at Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milan, since February 16, 2012.
Is member of Italian Society of Psycho-Oncology (SIPO), Italian Association of Pediatric Hematology and Oncology (AIEOP), and Italian Association of Clinical Psychology (AIP).
He is (co)author of more than 120 papers in peer-reviewed medical journals.

Serena Di Cosimo
Milan, Italy
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Breast Oncology

Lorenzo Ferrando
Genova, Italy
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Bioinformatics/Biostatistics
Dr. Lorenzo Ferrando is a computational scientist at the IRCCS Ospedale Policlinico San Martino in Genova, Italy. He obtained a PhD in 2021 in Translational Medicine from the University of Genoa, focusing on special and rare types of breast cancer, utilizing advanced Next-Generation Sequencing (NGS) techniques to uncover the genetic and epigenetic landscapes of the disease. In 2019, his expertise in genomics was further developed during a tenure at the Memorial Sloan Kettering Cancer Center in New York City, at The Jorge Reis-Filho Lab.
Since 2021, Dr. Ferrando works at the Translational and Integrative Genomics Research Lab, under the guidance of Prof. Gabriele Zoppoli. His research now focuses on pioneering early detection of breast cancer, through non-invasive techniques.
Moreover, Dr. Ferrando contributes to the AURORA Program, the most extensive biobanking initiative designed for the molecular characterization of metastatic breast cancer to investigate on progression and resistance mechanisms of the disease.

Andrea Ferrari
Milan, Italy
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Pediatric Oncology
Dr. Andrea Ferrari has been working since 1994 at the Pediatric Oncology Unit of the Istituto Nazionale Tumori of Milan.
He has dedicated his career in curing and studying children, adolescents and young adults with solid tumors. In particular, he tackled research projects dedicated to soft tissue sarcomas, pediatric rare tumors and adolescents/young adults projects. He worked as chair of various international cooperative groups, developing a large experience in leading and coordinating multidisciplinary working team. In the last years, he devoted himself also to the special needs of adolescents and young adults with cancer. He developed the “Youth Project” in his center. He is author or co-author of more than 550 papers published on international scientific journals, and 45 book chapters.

Claudia Gamondi
Losanna, Vaud, Switzerland
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Palliative and Supportive Care
Graduated in medicine and surgery in 1996, Claudia Gamondi obtained a specialization in medical oncology at the University of Pavia (Italy) in 2000. In 2013, she obtained a master’s degree in palliative medicine at the University of Bristol (United Kingdom). In 2016, she obtained the advanced training diploma in medicine palliative ISFM/FMH and in 2022 a doctorate at the University of Lancaster (Royaume-Uni, UK).
After working as an assistant doctor and then as clinic head of the Palliative Care Department of the Institute of Oncology of Italian Switzerland, she continued her career between Biella and England. In 2014, she held the position of medical director of the Palliative Care and Support Service of the Institute Oncology of Italian Switzerland. In 2020, she was appointed affiliated professor at the Faculty of Biomedical Sciences from the University of Italian Switzerland. Since October 2023, she has been head of Palliative Care and Support Service at CHUV and full professor at U N IL.
Claudia Gamondi has been teaching for over 20 years. She collaborated in developing pre- and post-graduate courses for doctors, nurses and other professionals involved in palliative care. She has a particular interest in training young professionals in this discipline, having supervised numerous colleagues in their healthcare palliative careers. She is president of SwissEduc (palliative care training group) and was a member of the committee of swiss palliative (Swiss Society of Medicine and Palliative Care) for more than ten years.
Research: Claudia Gamondi is committed to the development of palliative care research at the national and international level. She has conducted research on various palliative care subjects and she is now eager to strengthen research in the field of assisted suicide. In particular, she focuses on clinical, social and institutional factors that may influence the experiences of patients, family members and professionals regarding the assisted suicide process. She is also attentive to the obstacles and factors facilitating access to early palliative care.

Stefania Gori
Negrar di Valpolicella, Verona, Italy
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Breast Oncology
Director of the Department of Oncology and Medical Oncology at IRCSS Sacro Cuore Don Calabria in Negrar di Valpolicella since 2013, she has authored more than 200 publications in scientific journals, participated as a speaker in more than 250 congresses and has been scientifically responsible for about 100 regional and national scientific congresses. Her main interest is breast cancer.
She is scientific head of the School of Clinical Research Methodology in Negrar.
She was National President of the Italian Association of Medical Oncology from 2017 to 2019 and then President of the AIOM Foundation until 2021.
She is President of the Italian Association of Multidisciplinary Oncology Groups-AIGOM.
She has been a member of the Board of Directors of Alliance Against Cancer (ACC) since 2024.
She is a member of ASCO, ESMO, AIOM, GOIRC, MITO, GIM.

Alessandro Gronchi, MD
Milan, Italy
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Sarcoma
Chief of Sarcoma Service
Chair of the Department of Surgery
Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute)
Alessandro Gronchi MD received his MD degree from Milan University in 1992, completed his residency training in General Surgery in 1997 and a fellowship in Surgical Oncology in 1998. He holds the National Scientific qualification for full professor of General Surgery. He is chief of the Sarcoma Service since 2001 and chair of the department of Surgery since 2022 at the National Cancer Institute – Milan – Italy.
He is involved in all institutional research activities on sarcoma, which include neoadjuvant therapies in extremity and retroperitoneal sarcomas, new targets for specific STS types, genomic characterization of DF and its impact in tumor progression, mechanisms of resistance to therapy in GIST. He is the Principal Investigator of several Italian and International trials on STS, DF and GIST.
He serves as member of the board of directors of the Italian Sarcoma Group, member of the board of directors of the European Society of Surgical Oncology 2020-2024; international representative on the executive council of the SSO 2021-2024; member of the Sarcoma Task Force of the European Society for Medical Oncology. He was chair of the EORTC Soft Tissue and Bone Sarcoma Group (2015-2017), president of the Connective Tissue Oncology Society (2016); president of the Italian Society of Surgical Oncology (2019-2021). He is member of the European Surgical Association, the American Society of Clinical Oncology and honorary member of the Polish Society of Surgical Oncology. He is one of the initiators of a global collaborative effort on retroperitoneal sarcoma (Trans-atlantic Australasian RetroPeritoneal Sarcoma Working Group, TARPSWG), which involves over 180 institutions worldwide. Dr. Gronchi has authored more than 500 scientific publications (Scopus HIndex 100), serves as Associate Editor of Annals of Surgical Oncology, Journal of Surgical Oncology, Critical Reviews in Oncology/Hematology, Therapeutics Advances in Medical Oncology; Updates in Surgery.

Giuseppe Lo Russo
Milan, Italy
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Thoracic Oncology
Dr. Giuseppe Lo Russo is a Medical Oncologist in the Thoracic Unit at the Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.
He is very expert in the management of patients with thoracic tumors. He obtained a PhD in Medical Oncology at the “Sapienza” University of Rome, inherent translational research in the field of oncology. During his training, he gained experience in various public hospital institutions in Italy, including the Santa Maria Goretti hospital in Latina, the Umberto I polyclinic in Rome and the National Cancer Institute in Milan. His professional career also took him in the United States, to the Comprehensive Cancer Center of the Ohio State University. Here he carried out biomedical research focused on thoracic tumors, demonstrating a particular interest in preclinical cancer research. At the thoracic oncology unit of Fondazione IRCCS Istituto Nazionale Tumori of Milan, he is involved in numerous clinical and translational research projects and he actively participates in phase I, II and III clinical trials as principal or sub-investigator. In addition to his technical skills, Dr. Giuseppe Lo Russo is also an organized person with excellent interpersonal and communication skills. He is an Italian native speaker and has excellent knowledge of English (reading, writing and speaking). He is a member of important scientific associations, including the Italian Association of Medical Oncology (AIOM) and the European Society of Medical Oncology (ESMO). He is author of over 130 scientific publications in indexed international journals. He has also received recognition and awards for his academic excellence and contribution to oncology research.

Domenica Lorusso
Milan, Italy
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Gynecologic Oncology
Domenica Lorusso, MD, PhD, is Director of Gynaecological Oncology Unit at Humanitas Hospital San Pio X, Milan, and Full Professor of Obstetrics and Gynaecology, Humanitas University, Rozzano (MI). Prof Lorusso has been involved in gynecological oncology research for more than 25 years and has conducted or participated in approximately 250 phase I-IV clinical trials in gynecological malignancies. At present she is Principal Investigators of more than 60 studies. Prof Lorusso is responsible of the Clinical Trials Committee of the MITO (Multicenter Italian Trials in Ovarian Cancer and Gynaecological Malignancies) Group, which includes more than 150 Italian centers involved in gynecological oncology research. She is member of Board of Directors of Gynaecological Cancer Intergroup including 23 international research groups involved into the promotion and conduction of high-quality clinical trials to improve outcomes for women with gynecological cancers.
Prof Lorusso is also active member of ENGOT (European Network of Gynaecological Oncological Trial groups) an international organization which coordinates and promotes clinical trials within Europe for patients with gynecological cancers where she chairs the Gynecological cancer Academy.
She is member of Board of Director of European Society of Gynecology Oncology (ESGO). She has also co-authored about 300 international oncology publications. She is author of national and international guidelines on treatment of ovarian, cervical and endometrial cancer. Dr Lorusso’s key goals are to ensure best treatment to all patients and promote the clinical research, international trial collaborations and educations.

Monica Niger
Milan, Italy
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Gastrointestinal Oncology
Dr. Monica Niger is a medical oncologist of the Gastrointestinal cancer Unit at Fondazione IRCCS Istituto Nazionale dei Tumori di Milano (INT) and she works specifically with patients affected by biliary and upper gastrointestinal cancers.
Dr. Niger completed her fellowship in Medical Oncology at INT in 2017, after receiving a comprehensive clinical and research training with a specific focus on GI and translational oncology. With this aim, she spent a year in Dr. Ranjit Bindra’s laboratory at Yale University, where she was directly involved in DNA repair deficiency and IDH1/2 mutation-related projects both in the laboratory and in the clinical setting. Together with Dr. Bindra and his mentor Dr. LoRusso, she developed and wrote a phase II trial aimed at assessing the efficacy of olaparib for the treatment of recurrent/progressive IDH1/2-mutant solid tumors, which has a specific cholangiocarcinoma cohort (NCT03212274). After that, Dr. Niger started working as a medical oncologist at INT and she pursued national and international collaborations to better clarify the prognostic and predictive impact of specific molecular alterations, such as MGMT methylation, IDH1 mutations, BRCA 1/2 mutations and BRAF mutations on the history of patients affected by biliopancreatic cancers.
Dr. Niger’s contribution to clinical cancer research is documented by more than 70 research papers published in peer-reviewed journals that attest her ability to successfully collaborate both in clinical and translational research projects. Moreover, she has been involved as a principal investigator and sub-investigator in numerous Phase I, II and III clinical trials. Furthermore, she was granted the Young Researcher Award assigned by INT in 2018.
Finally, Dr. Niger was integral part of the team designing and conducting various academic clinical trials and she
designed and is the national principal investigator of the PURITY study (NCT06037980), which is a no-profit, multicentre, randomized phase II/III trial aimed at evaluating the efficacy of the combination of gemcitabine, cisplatin and nabpaclitaxel (GAP) as neoadjuvant treatment in patients with resectable biliary tract cancer at high risk for recurrence.

Ester Orlandi
Pavia, Italy
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Radiotherapy
Chief of Clinical Department at National Center for Oncological Hadrontherapy (Fondazione CNAO), Pavia, Italy and Researcher at University of Pavia; Department of Clinical, Surgical, Diagnostic, and Pediatric Sciences, Pavia, Italy
Dr. Ester Orlandi has more than 20 years’ experience in radiation oncology in Head & Neck cancer.
She currently is type-B Researcher at the University of Pavia and holds the positions as Chief of the Clinical Department at CNAO. She is focused in managing rare tumors, particularly in the H&N, and is skilled in advanced radiotherapy techniques, side effects modelling, and personalized therapy. She focuses on testing new combinations of beam qualities and drugs to improve cancer treatment effectiveness.
She is involved in several Italian and international clinical trials and registries as PI or sub investigator.
Since March 2020 up to today, she is a representative of the EORTC H&N group for the Radiation Oncology Scientific Council (ROSC). Since January 2021 she is ESMO faculty member for the Head and Neck Cancer group and since December 2022 is Scientific Committee member for ESMO 2024. Since April 2019 up to today she is Counselor of the Italian Association of Head and Neck Oncology (AIOCC). She has been appointed as the senior scientific advisor at Shanghai Proton and Heavy Ion Center (SPHIC). She is the author and coauthor of 7 book chapters, 229 scientific journal articles impacted peer review journals. H-index 30.

Fedro A. Peccatori
Milan, Italy
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Gynecologic Oncology
Fedro A. Peccatori is a senior medical oncologist with a keen interest in women’s cancer. He is Director of the Fertility and Procreation Unit at the European Institute of Oncology in Milan, Italy and holds a tenure as adjunct Professor in the Medical Oncology Postgraduate Programme at the University of Milan. He has a strong scientific curriculum, with more than 300 publications in international journals and an H index of 57. His research activities deal with fertility preservation and counselling of adolescents and young adults with cancer, clinical and molecular characterization of pregnancy associated cancers, innovative treatment of breast and gynaecological malignancies, oncological education and oncohumanities. Since 2016, he serves as Scientific Director of the European School of Oncology and since January 2022 sits in the board of AIFET as counsellor. His motto is: be hungry for knowledge, but also for justice and compassion.

Paola Perego
Milan, Italy
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Preclinical Pharmacology
Dr. Perego (180 publications; H index 49) is a Senior Staff Scientist at the Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy. She obtained a degree in biology, a diploma of Specialization in Applied Genetics, and a PhD in Translational Biomedicine. She has the National Scientific qualifications as full professor of Pharmacology and of Applied Biology, and is Adjunct Professor at the University of Insubria for teaching Novel Anticancer Therapies. Her main activity has been the investigation of the molecular bases of antitumor agent efficacy with a contribution to the preclinical development of conventional and targeted agents, setting up collaborations with academic institutions, resulting in patents. In this regard, she contributed to the discovery of a new class of proteasome inhibitors targeting the 19S subunit (D’Arcy P. et al., Nat Med. 2011).
Her current focus is the overcoming of drug resistance by targeting tumor molecular alterations in various tumor types including ovarian cancer. In this disease, she contributed to the elucidation of the role of p53 in drug resistance, with emphasis on the importance of p53 mutations in mediating cisplatin resistance (Perego, P., et al., Cancer Research, 1996). She has deeply investigated the mechanisms of resistance to platinum agents (Rottenberg, S., Disler, C., Perego, P. Nature Reviews Cancer, 2021).
Dr. Perego is a member of the EORTC-PAMM (Pharmacology and Molecular Mechanisms) Group from 2005 and of the PAMM committee from 2015. She participates in the Institutional Scientific Advisory Board and in the scientific board of the G. Berlucchi Foundation (Italy), which funds cancer research. Besides being a Section Editor of Tumori Journal (from 2015), she is a member of the Editorial Board of Int J Oncol (from 2009), Curr Med Chem (from 2016), Int J Mol Sci (from 2018) and J. Thorac Oncol (from 2020). Dr. Perego is an active manuscript referee and authored eight book chapters in the field of molecular pharmacology of antitumor agents (ed. Humana Press; UTET, J. Wiley & Sons).

Giuseppe Procopio
Milan, Italy
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Gastrointestinal Oncology
Director of the Genitourinary Cancer Unit of the Medical Oncology Department at Fondazione IRCCS Istituto Nazionale dei Tumori – Milan, Italy
Giuseppe Procopio, Full Professor and MD is currently Director of “Programma Prostata” (a Scientific Directorate program) and Head of the Genitourinary Cancer Unit of the Medical Oncology Department at Fondazione IRCCS Istituto Nazionale dei Tumori – Milan, Italy, where his principal area of expertise is clinical research in Genitourinary Oncology.
In 1992, Dr Procopio received his medical degree in medicine from the University of Messina and in 1997 the specialty degree in Medical Oncology. He has held clinical positions at the Fondazione IRCCS Istituto Nazionale de Tumori in Milan, where he was appointed Associate Researcher of the Medical Oncology Division from 1997 to 2000, later becoming staff physician since 2013 when he was appointed Head of Genitourinary Cancer Unit.
He is the coordinator of numerous national and international multicenter research protocols in the field of onco-urology, focusing in particular on kidney cancer, prostate cancer, and immunotherapy.
Since 2000, he has been appointed Scientific Advisor by several Pharmaceutical Companies and Member of Scientific Committees by several Scientific Organization.
He is currently a member of prominent medical oncology associations (ASCO, ESMO, AIOM, etc.) and was the Head of the Oncology Division at the Ospedale Maggiore in Cremona from May 2022 to October 2022.
He is the elected President of FICOG (Italian Federation of Cooperative Oncology Groups) and President of Meet-URO (Italian network of Urological Oncology).
He coordinates the AIOM guidelines for kidney tumors and serves on the committee responsible for drafting the ESMO European guidelines for kidney and prostate tumors.
He is the author or co-author of over three hundred publications in medical oncology for the most prestigious journals in the field, with an H-index of 43.

Antonio Silvani
Milan, Italy
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Neuro-Oncology

Carlo Sposito
Milan, Italy
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Gastrointestinal Oncology
Professor Carlo Sposito is a HPB (Hepato-Pancreato-Biliary) surgeon, currently serving at the G.I. Surgery and Liver Transplantation Unit of the Fondazione IRCCS Istituto Nazionale dei Tumori (National Cancer Institute) in Milan. In addition, he is Associate Professor of General Surgery at the Department of Oncology of the University of Milan. He is Fellow of the European Board of Surgery (FEBS) in HPB.
He specialized in General Surgery in 2009 at the University of Milan, after training at the three major Transplant Centers in Milan and at the Hospital Clinic in Barcelona. During his surgical career, he has performed more than 1200 major HPB surgical procedures, with a particular focus on mini-invasive laparoscopic and robotic approaches.
Since 2007, Professor Sposito has been Principal Investigator and Co-investigator of several national and international multicenter studies in the area of hepatobiliary and transplant oncology. He has authored and coauthored more than 100 publications in peer-reviewed international medical journals, with a current H-Index of 32 and over 4,500 citations. In addition, he holds editorial positions as the section editor of Gastrointestinal Oncology for Tumori Journal, Cancer Treatment and Research Communications, and Gastrointestinal Tumors.
Professor Sposito is member of several international and national scientific societies, and forms part of the governing council of AICEP (Associazione Italiana di Chirurgia Epato-bilio-pancreatica).

Annalisa Trama, MD, PhD
Milan, Italy
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Epidemiology and Prevention
Annalisa Trama, is the Director of the Evaluative Epidemiology Unit at the Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy.
Her research activities focus on rare cancers and adolescent and young adult cancers.
She is an expert in population-based research including population-based cancer registries and administrative datasets. She was a founder of RARECARE (surveillance of rare cancers in Europe) which proposed a definition for rare cancer.
She coordinates the clinical registry of EURACAN, the European Reference Network on rare adult solid cancers.
She was the founder of RARECAREnet Asia, a collaboration between European and Asian population-based cancer registries (CRs) on rare cancers.
In the area of rare cancers, she co-coordinated the Joint Action on Rare Cancers (JARC), carried out between 2016 and 2019 within the framework of the Third Health Programme
with 34 partners and 18 EU Member States.
She was a founder of the first Italian adolescent and young (AYA) cancer survivor cohort and she coordinate the Steering committee of this cohort. She is a member of the Scientific Coordination of EUROCARE (surveillance of cancer patients in Europe). She is PI of national and international projects exploiting secondary use of real-world data (e.g. electronic health record, administrative database, clinical registries, population-based registries) and use of innovative solutions (e.g. data fusion; AI approach for defining causal relationship; AI solution to support interoperability of data sources).
She is (co)author of more than 100 papers in peer-reviewed medical journals.

Andrea Vingiani
Milan, Italy
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Molecular Pathology
Dr. Andrea Vingiani, Pathology Assistant at the Department of Advanced Diagnostics, and Assistant Professor in Pathology at UNIMI.
Dr. Andrea Vingiani is a fully trained pathologist with specialized expertise in breast and head & neck malignancies. His research focuses on identifying molecular lesions and predictive and prognostic factors. He is particularly involved in studying the role of inflammatory tumor infiltrates (TILs) in solid neoplasms and collaborates with the International Immuno-Oncology Biomarker Working Group, led by Roberto Salgado, Sherene Loi, and Carsten Denkert, which is dedicated to the study of TILs.
He is an active member of the Molecular Advisory Board and the Steering Committee of the international clinical trial AURORA (Aiming to Understand the Molecular Aberrations in Metastatic Breast Cancer), under the Breast International Group (BIG). This trial, led by Professor Martine Piccart, investigates somatic and germinal mutations in patients with metastatic breast cancer through mutational analysis by massive parallel sequencing (using a panel of 411 genes from ONCODNA S.A.).
He leads the Clinical Research Laboratory (CRAB) at Fondazione IRCCS Istituto Nazionale dei Tumori (INT) in Milan, a team of biologists and technicians dedicated to translational research. His group supports various research teams in histopathological diagnosis, immunohistochemical analysis (using Dako and Ventana platforms), and transcriptomic analysis (with Nanostring nCounter). They also conduct independent research projects, including epigenetic and transcriptomic characterization of breast carcinoma and clinical studies evaluating metabolic interventions in breast cancer treatment. His team performs spatially resolved transcriptomic analysis using the GeoMx Digital Spatial Profiler (Nanostring) and single-cell analysis (10x Genomics Chromium), closely collaborating with the institutional bioinformatics facility.
As the coordinator of the INT Molecular Tumor Board, Dr. Vingiani provides gene variant annotations and targeted therapy recommendations for 1,500 advanced/metastatic cancer patients annually, utilizing NGS testing on Thermofisher Ion S5 and Illumina Nextseq500 platforms.
Dr. Vingiani’s research is documented in 85 works published in indexed journals, with over 3,400 citations and an H-index of 24 (Scopus). His extensive contributions to the field underscore his commitment to advancing cancer research and improving patient outcomes.

Gabriele Zoppoli
Genova, Italy
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Molecular Pathology

